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Endocrine Abstracts

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ea0063gp155 | Cushing's | ECE2019

Endocrine immune-related adverse events following immune checkpoint inhibitors in patients with advanced melanoma: single-center retrospective analysis

Kassi Eva , Angelousi Anna , Asonitis Nikos , Petychaki Foteini , Diamantopoulos Panayiotis , Anastasopoulou Amalia , Benopoulou Olga , Gogas Helen

Introduction: Immune-check point inhibitors (ICPis) has been shown to significantly improve survival in patients with advanced melanoma. Immune-related endocrinopathies (irEs) and in particular hypophysitis and thyroid dysfunction have been well described with an incidence varying from 9–17% and 3.8–13.2% respectively.Methods: This is a retrospective analysis of irEs in 325 (190 men) patients with melanoma receiving ICPis (PD-1/PDL-1 or CTLA-4 ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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